“Comprehensive NFL Week 6 injury report with key fantasy football updates, player statuses, and return outlooks to guide your lineup decisions.”
Injuries decide fantasy seasons as much as draft day. Winning requires sharp roster management and constant awareness of changing statuses. This NFL week 6 injury report focuses on defense first for IDP formats, then finishes with a fast offensive rundown. Every note below comes directly from this week’s transcript and reflects the latest context presented there.
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Titans: Jeffery Simmons Tracks Toward Playing
Jeffery Simmons gave a midweek scare. He did not practice on Wednesday. He returned to a limited practice on Thursday. The expectation is that he is good to go. He finished last week’s game, which usually bodes well.
The matchup this week could offer production opportunities. Simmons remains a core piece up front. This NFL Week 6 injury report leans optimistic based on the practice trend and game finish. The update signals an upward arrow for managers who needed clarity.
Jets: Jermaine Johnson Nearing Return
Jermaine Johnson injured his ankle in Week 1 and missed multiple weeks. He is finally back at practice in a limited fashion. There is a legit shot to play in London this weekend. The timeline and phrasing point to a high ankle or eversion-type injury. High ankle sprains involve the ligaments between the tibia and fibula called the syndesmosis. Even minor cases often take four to six weeks.
If Johnson logs a full practice on Friday, a start is possible. However, his first game back presents a tough matchup. Consider a cautious approach and evaluate how he looks. This NFL Week 6 injury report shows progress while urging patience for one more week if depth allows.
Steelers Secondary: Opposite Trends
Joey Porter Jr. dealt with a hamstring injury a couple of weeks ago. He logged back-to-back full practices after the bye. That trend points to playing on Sunday. Hamstrings are tricky because they feel better before they are healed. Re-injury risk is higher in the two weeks after returning.
Jalen Ramsey picked up a hamstring injury in London a couple of weeks ago. He opened the week with two straight days of “did not practice”. Expect at least another week out. The NFL Week 6 injury report shows the Steelers’ secondary moving in two different directions at once.
Steelers Edge: Alex Highsmith Upgrades
Alex Highsmith has a high ankle sprain. He moved from limited to full and is in line to return this week. A rotation with Nick Herbig and T.J. Watt is likely. The opposing offensive line and a rookie quarterback suggest pressure opportunities.
For IDP, Highsmith’s upgrade is significant. The NFL Week 6 injury report frames him as trending back toward a usable workload with rotational support easing the return.
Concussions: Timelines and Two Key Cases
A concussion is a mild traumatic brain injury affecting processing and decision-making. Early in seasons, returns often skew cautious. The protocol involves five steps. The last two steps require limited, then full practice without symptoms. Thursday is usually a key day for progress.
Justin Reed suffered a concussion last week and was ruled out of that game. He practiced limited on Wednesday and full on Thursday. Barring setbacks, he should play Sunday. Tyrel Dodson did not practice. Without at least a limited session by Thursday, players are typically ruled out. Rare simulated Saturday clearances are not expected here. This NFL Week 6 injury report highlights both divergent paths.
Patriots: Christian Gonzalez Maintenance Day
Christian Gonzalez returned last week and played a huge role. He showed up limited with a hamstring. This was described as a pre-planned rehab-focused day rather than a setback. He did stretches and some individual work, then shifted back to rehab.
The expectation is that he plays if Friday goes well. Watch for a full practice confirmation. The NFL Week 6 injury report lists him as trending positive, with the limitation attributed to maintenance.
Chargers: Denzel Perryman Pointing Up
Denzel Perryman likely suffered a high ankle sprain early in the year. He has missed several weeks. However, he is now upgraded to a full participant and should be back Sunday off injured reserve. He slots back into the Chargers’ linebacker corps next to Daiyan Henley.
His recent form has been middling, but today’s full practice is an optimistic sign. This NFL Week 6 injury report marks Perryman as a key returning piece with immediate relevance.
Lions Secondary: Two Different Timelines
Terrion Arnold has managed a multi-week shoulder issue with in-and-out availability. He sought second opinions. Surgery was on the table, but the second opinion recommended no surgery. He will be out for a couple of weeks and is expected back within a month. Do not expect him this week.
Kerby Joseph has a knee issue with back-to-back did not practices. It is not reported as long-term. He still has a shot to play. Friday practice status will be decisive. If he does not practice on Friday, a pivot is needed. This NFL week 6 injury report underlines a near-term absence for Arnold and a true questionable tag for Joseph.
Bills: Matt Milano Setback
Matt Milano re-aggravated a pec injury after returning. He did not practice on Thursday. He is likely out Monday against the Falcons and could miss multiple weeks. The team signed Baylon Spector to bolster depth. Re-aggravation means previously damaged muscle was stressed again. That usually does not resolve quickly.
Expect redistribution of work among available linebackers. The NFL week 6 injury report urges caution, as repeated aggravation risks extend timelines.
Seahawks: Devon Witherspoon Concerns
Devon Witherspoon has battled a knee issue and missed last week. He has two straight “did not practice” this week. He underwent an MRI to evaluate the problem. The situation feels ominous, and expectations point to him sitting this week against Jacksonville.
Several weeks out is possible. The NFL Week 6 injury report lists multiple red flags, including the MRI and the consecutive absences.
Falcons: A.J. Terrell Jr. Eyes Monday Night
A.J. Terrell has been out for several weeks with a hamstring. After the bye, he returned to practice limited. He personally stated he will be playing on Monday night. With two more practices before Monday, chances look strong.
A return would stabilize coverage and help force offenses to adjust. This NFL week 6 injury report views Terrell’s arrow as pointing up based on his statement and practice trajectory.
Ravens: Kyle Hamilton Trending Toward Return
Kyle Hamilton missed one game after a practice groin injury. He moved from limited Wednesday to full Thursday. He is definitely in line to be back Sunday. Groin refers broadly to lower abdominal and adductor structures. Even mild strains require care due to multidirectional stress.
There are several other moving parts. Kyle Van Noy returns. Roquan Smith is not practicing and is unlikely. Marlon Humphrey went limited today after a “did not practice” yesterday and might be back. Hamilton remains the quarterback of the secondary and a playmaker everywhere. The NFL Week 6 injury report signals a major boost if he is active.
Offensive Rundown: Fast Hits for Lineup Moves
Lamar Jackson did not practice again this week. He is way more doubtful than questionable. The expectation is a holdout through the bye. Snoop Huntley may start, not Cooper Rush.
Kyler Murray had back-to-back did not practices after leaving with knee and foot concerns, then finished. If he practices on Friday, he can play, but he would be limited. Terry McCormick is still not practicing. It is not a good sign, though a Monday kickoff leaves two practices to go.
Jauan Jennings returned limited with ankle and rib issues and is expected to try on Sunday. Mike Mac Jones likely throws to him because Brock Purdy had a setback, logged two straight did not practices, and remains on injured reserve this week. Ricky Pearsall is not practicing with a PCL injury. Do not expect Kittle, Pearsall, or Purdy to be out there.
CeeDee Lamb and Chuba Hubbard are not practicing. Lamb’s high ankle seems close, but likely not this week. Both worked on the side. If no practice by Thursday, players are usually out Sunday. Rico Dowdle is noted after a monster 200-yard game last week for Carolina.
Xavier Worthy did not practice today after a full session yesterday. That leans precautionary, and he finished Monday’s game. Expect him to play, but watch closely. In Tampa Bay, Bucky Irving, Mike Evans, and Chris Godwin did not practice. Evans and Irving are at least a week away. Godwin has a fibula issue after playing two straight weeks, which is not a good sign. Do not expect at least two, if not all three, Buccaneers.
Final Word
The NFL week 6 injury report demands discipline and flexibility. Defensive moves drive IDP wins, but the late offensive notes can swing matchups. Track Friday statuses closely and prepare pivots where this transcript signals doubt. Smart, timely adjustments can turn injuries into an edge.
Thank you for reading this article from @IDP_Plus. This article was crafted with insights from the original podcast hosts, supported by AI tools, and shaped by our staff. For the full discussion and even more great content, be sure to check out the episode on YouTube. Follow the host @TheDegenDoc on the X!!


