Get expert NFL Week 1 odds insights and betting tips for 2025. Avoid hype and make smart wagers based on key matchups and spreads.
Week 1 of the 2025 NFL season brings value-based betting action for all games right from the season’s opening kick. Value-based bettors like myself like playing Week 1 odds card for several reasons. The one I like to focus on is simple. A reason of, nobody knows who is really good or bad just yet. Stop guessing for week 1 and take all UNDERDOGS.
Week 1 NFL Betting Tips You Can Lock In Today
When handicapping the upcoming Week 1 odds, avoid chasing hype and inflated spreads. The tip I would like to offer here is this. All Week 1 point spreads will be inflated. If you plan on wagering on week one, do yourself a favor and take ALL UNDERDOGS. Do it now, do it early, and do it often! Nobody knows who is good or bad. In the offseason, NFL rosters turn over dramatically. NFL odds are made with historical data and public sentiment. Since we do not yet have historical data for the new season, you can be assured that oddsmakers will leverage public sentiment and recency bias in setting point spreads. Use this to your advantage and lock in underdog bets. Not just a few underdogs but ALL underdogs.
Key Matchups and Week 1 Odds Strategy
Here are early odds and strategic angles on major Week 1 games:
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Philadelphia Eagles (-7.5) Vs Dallas Cowboys: Division rivals with both teams knowing each other well. Dallas will survive the juice Eagle fans throw their way and keep this one close throughout.
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New York Jets (+3.5) Vs Pittsburgh Steelers: The Jets stink, but the new coaching staff and fan base will treat this gem as if it were the Super Bowl. The media will hype this game up with Aaron Rodgers returning to MetLife Stadium. The Jets will have all the headline hype they need, plus you getting 3.5 points.
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Buffalo Bills (-2) Vs Baltimore Ravens (Sunday Night Football): The Buffalo Bills are going to be just fine. However, they lose this one outright. You do not need a legitimate reason. This pick is being made without reviewing opening day rosters. I know enough that these teams are about even… take the two points and roll the dice.
8 NFL Divisional Underdogs Week 1. @otlsports #football #betting #picks https://t.co/IzEsbPqght
— Vegas Sports Picks (@vegas_parlay) July 17, 2025
Conclusion: Roll With All Week 1 Underdogs
Feel fre to do deeper analysis on your IDP Fantasy Football Leagues. In terms of NFL 2025 week 1 odds, keep it simple. You do not need to overanalyze the market. Simply be aware that it will consist of inflated point spreads. Take advantage of the point spread inflation and ride with the underdogs. Do this just for the very first week.
Thank you for reading my 2025 NFL week 1 odds article. You can read more of my sports betting content on my IDP+ Author page. After that, feel free to connect with me on Twitter @MarcSaulino and follow @IDP_Plus to stay informed about everything NFL-relevant by becoming a member.
